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Tec-Control Chromatography Systems

Tests the radiochemical purity of specific Tc-99m-labeled radiopharmaceuticals.

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Description

For radiopharmaceutical quality control

Tec-Control Chromatography tests the radiochemical purity of specific Tc-99m-labeled radiopharmaceuticals. The accompanying chart shows which strips and solvents are required to perform each individual test. Some solvents must be purchased separately (see Sigma-Aldrich chart) due to hazardous material shipping restrictions.

Detailed instruction manuals are packaged with each strip container, although our Radiopharmaceutical QC Procedure Manual (151-000) explains paper chromatography in greater detail.

 

References:

Miniaturized Chromatographic Quality-Control Procedures for Tc-99m Radiopharmaceuticals; A. Michael Zimmer and Dan G. Pavel, Journal of Nuclear Medicine, Vol. 18/12, Dec. 1977, pg. 1230.

Technical Parameters Associated with Miniaturized Chromatography Systems; Raimund A. Taukulis, A. Michael Zimmer, Dan G. Pavel and Bhupendra A. Patel, University of Illinois Medical Center, Chicago, Illinois, Journal of Nuclear Medicine Technology, Vol. 7/1.

Solvents

RADIOPHARMACEUTICAL SOLVENT(S) REQUIRED* STRIPS REQUIRED
Aluminum Breakthru 150-781 10 µg/ml 150-782
Aluminum Breakthru 150-783 5 µg/ml 150-782
Bicisate (Neurolite™) Ethyl Acetate 99.% 150-130
Diphosphonate Acetone (HPLC Grade), Distilled H2O 150-001 & 150-005
Disofenin (Hepatolite™) 150-160, Distilled H2O 150-122 & 150-125
DMSA Acetone (HPLC Grade), 150-025
DTPA Acetone (HPLC Grade), Distilled H2O 150-001 & 150-005
Exametazine (Ceretec™) Ethyl Acetate 99.% 150-130
Fluorodeoxyglucose (FDG) Acetone (HPLC Grade) 150-127
Glucoheptonate Acetone (HPLC Grade), Distilled H2O 150-001 & 150-005
HDP; HMDP and Octreoscan™ HDP Acetone (HPLC Grade), Distilled H2O 150-001 & 150-126
MAA Acetone (HPLC Grade), 150-001
MAG3 (Mertiatide™) Acetone, (HPLC Grade), Chloroform 99.8% Tetrahydrofuran 99+% 150-951 & 150-952
MDP Acetone (HPLC Grade), Distilled H2O 150-001 & 150-005
Mebrofenin (Cholotec™) 150-160, Distilled H2O 150-122 & 150-125
Pyrophosphate Acetone (HPLC Grade), Distilled H2O 150-001 & 150-005
Sestamibi (Cardiolite™ and Miraluma™) Ethyl Acetate 99.% 150-991
Sulphur Colloid Acetone (HPLC Grade) 150-001
Tc-99m (reduced) Acetone (HPLC Grade), 150-001
Tc-99m Monoclonal  Antibodies 0.9% Saline 150-771
Tetrofosmin (Myoview™) Ethyl Acetate 99.% 150-971
In-111 Octreotide (Octreoscan™) 150-773 & 0.9% Saline 150-771 **
In-111 Monoclonal Antibodies 150-773 & 0.9% Saline 150-771 **
In-111/Y-90 Zevalin™ 0.9% Saline 150-772
I-131 Monoclonal Antibodies And Neutrospec™ 0.9% Saline 150-771

* See Sigma-Aldrich product matrix for solvents.
** Note: A Well Plate is suggested to perform QC on these radiopharmaceuticals
Contact Fisher Scientific Corp. 800-766-7000 / www.fishersci.com / Item #14-245-71

Manuals

Manual, Tec-Control Chromatography Strips, Red/Black, Operation
Manual, Tec-Control Chromatography Strips, Red/Brown, Operation
Manual, Tec-Control Chromatography Strips, Yellow, Operation
Manual, Tec-Control Chromatography Strips, Orange/Light Blue, Operation
Manual, Tec-Control Chromatography Strips, Green, Operation
Manual, Tec-Control Chromatography Strips, Gold, Operation
Manual, Tec-Control Chromatography Strips, Dark Green, Operation
Manual, Tec-Control Chromatography Strips, Blue, Operation
Manual, Tec-Control Chromatography Strips, Lime/Peach, Operation
Manual, Tec-Control Chromatography Strips, Teal, Operation
Manual, Tec-Control Chromatography Strips, Aluminum, Operation
Manual, Tec-Control Chromatography Strips, Pink, Operation

Support

Declaration of Conformity, Tec-Control Chromatography Kit and Accessories

SDS, 150-160 Solvent

Models and Ordering

Chromatography Strips

150-001 Strips, RED, 50/pkg
150-005 Strips, BLACK, 50/pkg
150-025 Strips, YELLOW, 50/pkg
150-122 Strips, ORANGE, 50/pkg
150-125 Strips, LIGHT BLUE, 50/pkg
150-126 Strips, BROWN, 50/pkg
150-127 Strips, GREEN, 50/pkg
150-130 Strips, GOLD, 50/pkg
150-771 Strips, DARK GREEN, 50/pkg
150-772 Strips, BLUE, 50/pkg
150-951 Strips, LIME, 50/pkg
150-952 Strips, PEACH, 50/pkg
150-971 Strips, TEAL, 50/pkg
150-991 Strips, PINK, 50/pkg
150-782 Strips, ALUMINUM, 50/pkg

Chromatography Solvents

150-160 Solvent, 20% Sodium Chloride, 30 ml
150-773 Solvent, DTPA, 5 ml
150-781 Solvent, Aluminum Standard, 5 ml, 10 µg/ml
150-783 Solvent, Aluminum Standard, 5 ml, 5 µg/ml

Related Items:

150-960 Developing Vials, Borosilicate Glass, 10 ml, 288/case
(used for most Tec-Control testing)
150-961 Developing Vials, Borosilicate Glass, 5 ml, 144/case
(used for Sestamibi & Tetrofosmin)
150-000 Procedure Manual, Radiopharmaceutical QC
066-533 Forceps, Curved, Locking, 9.5″ l (24.1 cm)
066-535 Forceps, Straight, Locking, 9.5″ l (24.1 cm)
066-536 Forceps, Curved, Non-Locking, 12.5″ l (31.7 cm)
Tec-Control Solvent Vendor:
Sigma-Aldrich Chemical Company
800-558-9160 / www.sigmaaldrich.com

Note: Customers outside the US should visit Sigma-Aldrich web site to locate a regional office.

Solvent Description Vendor Part #
Acetone HPLC Grade 27072-5
Ethyl Acetate 99.5% ACS Reagent 31990-2
Chloroform 99.8% ACS Reagent 31998-8
Tetrahydrofuran 99+% ACS Reagent 36058-9

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